N-heterocyclic Carbene (NHC) Chemistry

The   chemistry   of   N-heterocyclic   carbene   complexes   dates   back   to   almost   a   century ago,   even   though   a   scientific   look   into   their   true   geometries   and   properties   started in   mid   1950s.   Since   the   seminal   work   of   Arduengo   in   1991   on   the   generation   of stable   and   free   NHCs,   there   has   been   renaissance   in   the   field   of   carbene   chemistry that   led   to   the   discovery   of   important   metal-carbene   complexes   with   a   wide   range of   applications.   NHC   ligands   are   stable,   relatively   easy   to   prepare   and   metal-NHC bonds    are    strong.    Furthermore,    electronic    (singlet    or    triplet)    and    steric    (R) properties     in     NHCs     are     easily     tuned     by     the     modification     of     heteroatom substituents.   Because   of   these   fundamental   properties   they   are   highly   popular among   coordination   and   organometallic   chemists.   A   research   project   in   our   group deals   with   the   preparation   of   new   variations   of   NHC   ligands   and   study   of   their metal   complexation   in   particular   with   late   transition   metals.   Students   interested   in this   fascinating   filed   of   research   are   encouraged   to   have   a   look   at   the   following references to gain a general idea about NHC chemistry.   1. https://www.nature.com/articles/nature13384 3. https://pubs.acs.org/doi/abs/10.1021/cr4006439 4. https://pubs.acs.org/doi/10.1021/acs.chemrev.8b00067 5. https://pubs.acs.org/doi/10.1021/acs.chemrev.8b00791 2. https://www.sciencedirect.com/science/article/abs/pii/S0010854508001203

Bidentate and tridentate (“Scorpionate”) ligands

As   opposed   to   heterogeneous   catalysts,   homogeneous   catalysts   lack   durability   and ease   of   separation.   Despite   these   shortcomings,   homogeneous   catalysts   are   more selective   and   reaction   pathways   in   a   homogeneously   catalysed   reaction   are   easier   to study.   Ligands,   in   particular   “actor   ligands”   play   an   important   role   in   the   reactivity   of metal   center/centers   in   a   metal   complex.   Among   scorpionate   ligands,   borate-based ligands   with   softer   donor   atoms   such   as   sulfur   (Y   =   S)   have   persuaded   coordination chemists   to   develope   complexes   of   later   electron   rich   and   low   valent   transition metal   ions   such   as   copper.   A   pictorial   description   of   this   type   of   ligands   is   shown on    the    right.    We    are    particularly    interested    in    boron    containing    or    borate-based ligands,   where   it   can   act   as   an   electron   acceptor   (Z-type)   ligand.   Second   research project   in   our   group   deals   with   the   preparation,   structural   characterization   and investigation   into   the   catalytic   properties   of   metal   complexes   derived   from   borate- based   S   or   P   donor   ligands.   Important   references   relevant   to   this   topic   are   shown below. 1. https://pubs.acs.org/doi/abs/10.1021/ja00989a017 2. https://pubs.rsc.org/en/content/articlelanding/2011/dt/c0dt01181a 3. https://www.sciencedirect.com/science/article/pii/S0022328X12003713 4. https://pubs.acs.org/doi/10.1021/om040114%2B 5.   https://pubs.rsc.org/en/content/articlelanding/2012/CS/c2cs15346g#!divAbstract 6. https://www.sciencedirect.com/science/article/pii/S0065305516300028 7. https://pubs.rsc.org/en/content/articlelanding/2016/CS/C5CS00697J#!divAbstract

Teaching

General Notes • Class   notes   will   cover   exams;   however,   students   are   advised   to   get   a   copy   of   the   references shown below for further reading and learning. • Grades will be based on two exams (mid-term and final) and homework problem sets. • Problem   sets   will   be   sent   out   via   email.   They   will   be   collected   and   graded.   Answers   to   problem sets will be provided in the following class period.

M.Sc. Level Courses

Advanced Inorganic Chemistry Topics:   This   course   will   introduce   fundamentals   of   an   upper-level   Inorganic   chemistry   course.   First, basics    of    bonding    theory    (VSEPR,    Crystal    and    Ligand    field    theories,    MO    theory)    in    Inorganic compounds   will   be   introduced.   In   the   following   discussions,   basics   of   symmetry   and   group   theory will   also   be   introduced.   The   topic   of   symmetry   is   extremely   important   in   understanding   molecular properties   of   organic   and   inorganic   molecules   including   optical   and   spectral   properties.   Therefore, plenty   of   time   will   be   dedicated   for   covering   this   topic.   Other   relevant   topics   such   as   donor-acceptor (acid-base) chemistry and diverse aspects of coordination chemistry will also be covered. References: 1. F. A. Cotton and G. Wilkinson, Advanced Inorganic Chemistry, 6 th  edn., Wiley-Interscience, 1999. 2.   J.   E.   Huheey,   E.   A.   Keiter,   R.   L.   Keiter,   O.   K.   Medhi,   Inorganic   Chemistry,   4 th    edn.,   Pearson   Education, 2006. 3. F. A. Cotton, Chemical Application of Group Theory, 3 rd  edn., Wiley-Interscience publication, 1990. 4.   D.   F.   Shriver,   P.   W.   Atkins,   C.   H.   Langford,   Inorganic   Chemistry,   5th   edn.,   Oxford   University   Press, 2010. 5. Gary L. Miessler, Paul J. Fischer, Donald A. Tarr, Inorganic Chemistry, 5th edition, Pearson, 2013. Spectroscopy in Inorganic Chemistry I Topics:   This   course   will   introduce   fundamentals   and   concepts   necessary   to   characterize   coordination and   organometallic   compounds.   First,   fundamental   aspects   of   characterization   methods   in   inorganic chemistry   will   be   introduced.   Basics   of   Nuclear   Magnetic   Resonance   (NMR)   spectroscopy   will   then   be covered   in   detail.   Topics   such   as   the   basis   of   this   technique,   energy   levels   in   NMR,   instrumentation, chemical shifts, different orders of coupling, relaxation, etc. will be covered throughout this course. References: 1) Physical Methods for Chemists, Russell S. Drago, Saunders College Pub., 1992 2)    Characterization    Methods    in    Inorganic    Chemistry,    Mark    T.    Weller,    Nigel    A.        Young,    Oxford University Press, 2017 Spectroscopy in Inorganic Chemistry II Topics:   As   a   follow-up,   the   focus   in   this   course   will   be   on   vibrational   spectroscopy   techniques   (IR   and Raman), Electronic absorption (UV), Emission spectroscopy and Mass spectrometry techniques. References:  1) Physical Methods for Chemists, Russell S. Drago, Saunders College Pub., 1992 2)    Characterization    Methods    in    Inorganic    Chemistry,    Mark    T.    Weller,    Nigel    A.        Young,    Oxford University Press, 2017 Kinetic and Mechanism of Inorganic Reactions I Topics:   The   determination   of   rate   law   through   determination   of   relation   between   the   rate   of   a reaction   and   reactant   concentration   will   be   the   main   focus   of   this   course.   The   majority   of   topics   in chapter 1 and Chapter 2 from Reference no. 1 will be covered.     References: 1)   Kinetics   and   Mechanism   of   Reactions   of   Transition   Metal   Complexes,   2 nd    Edition,   R.G.   Wilkins,   2002 Wiley-VCH Verlag GmbH & Co. KGaA 2) Chemical Kinetics and Reaction Mechanisms, 2 nd  Edition, James H. Espenson, McGraw Hill, Inc. Kinetic and Mechanism of Inorganic Reactions II Topics:   Selective   topics   from   chapters   3   and   4   of   R.   G.   Wilkins’s   book   such   as   the   experimental methods    for    the    determination    of    a    rate    law,    substitution    reactions    and    oxidation-reduction reactions will be taught in detail. Chapter 12 of reference no. 2 will also be covered. References: 1)   Kinetics   and   Mechanism   of   Reactions   of   Transition   Metal   Complexes,   2 nd    Edition,   R.G.   Wilkins,   2002 Wiley-VCH Verlag GmbH & Co. KGaA 2) Gary L. Miessler, Paul J. Fischer, Donald A. Tarr, Inorganic Chemistry, 5th edition, Pearson, 2013. Organometallic Chemistry I Topics:   The   aim   of   this   course   is   to   introduce   students   with   principles   and   logics   of   Organometallic chemistry.   Organometallic   compounds   are   defined   as   metal   complexes   with   at   least   one   metal   - carbon   bond.   Catalysts   based   on   organometallic   compounds   have   a   long   history   of   application   in   the synthesis   of   small   and   large   (polymer)   organic   molecules   and   depending   on   the   type   of   metal   centers and   orbitals   involved   [(main   group   (s,   p),   transition   (d)   or   Lanthanides   and   Actinide   series   (f)],   they could   involve   in   diverse   reaction   pathways.   First,   important   ligand   types   and   their   nature   in   terms   of softness   or   hardness,   bonding   types   in   organometallic   compounds   and   electron   counting   principles will   be   introduced.   Next,   principles   of   important   reactions   types   relevant   to   organometallic   chemistry including oxidative-addition, reductive elimination, insertion and elimination reactions will be taught. References: 1.   C.   Elschenbroich   and   A.   Salzer,   “Organometallics:   A   Concise   Introduction,”   2nd   Edition,   Wiley-VCH, Weinheim, 1992. 2. Crabtree, R. H. The Organometallic Chemistry of the Transition Metals , Wiley; 5 Edition, 2009 Organometallic Chemistry II Topics:   As   a   follow-up   course,   other   important   topics   such   as   metal-ligand   multiple   bonding,   relevant theories, and homogeneous catalytic reactions by organometallic compounds will be covered.    References: 1.   C.   Elschenbroich   and   A.   Salzer,   “Organometallics:   A   Concise   Introduction,”   2nd   Edition,   Wiley-VCH, Weinheim, 1992. 2.   Crabtree,   R.   H.   The   Organometallic   Chemistry   of   the   Transition   Metals ,   Wiley;   5   Edition   (April   6, 2009).

Ph.D. Level Courses

Catalytic Reactions Topics: Most sections from chapters 1-4 of the following reference will be covered during this course.   References:

1.   

Catalysis:   

An   

Integrated   

Textbook   

for   

Students,   

Ulf   

Hanefeld,   

Leon   

Lefferts,   

2018   

Wiley-VCH,

Weinheim,

 

Germany

Structure and Bonding Topics:    Simple    bonding    theory,    principles    of    molecular    orbitals,    topics    relevant    in    coordination chemistry such as structures, isomers and also bonding in coordination complexes will be covered. References: 1. Gary L. Miessler, Paul J. Fischer, Donald A. Tarr, Inorganic Chemistry, 5th edition, Pearson, 2013.

2. Guillermo Gonzalez-Moraga, Cluster Chemistry: Introduction to the Chemistry of Transition Metal

and Main Group Element Molecular Clusters, Springer; 1993 edition.

Advanced Organometallic Chemistry Topics:   Most   topics   from   chapters   2   to   12   of   ref.   no.   2   will   be   covered   during   this   course.   Selected articles   from   ACS   Organometallics   with   subjects   ranging   from   fundamental   organometallic   reactions and mechanistic studies will also be discussed. References: 1.   C.   Elschenbroich   and   A.   Salzer,   “Organometallics:   A   Concise   Introduction,”   2nd   Edition,   Wiley-VCH, Weinheim, 1992.

2.  

Crabtree,  

R.  

H.  

The  

Organometallic  

Chemistry  

of  

the  

Transition  

Metals

,  

Wiley;  

5  

Edition  

(April  

6,

2009).

3.  

J.  

P.  

Collman,  

L.  

S.  

Hegedus,  

J.  

R.  

Norton  

and  

R.  

G.  

Fi  

“The  

Principles  

and  

Applications  

of  

Transition

Metal Chemistry” (University Science Books).

Current Ph.D. Students

• Meysam    Kakavand    (2019-present),    Research    topic:    Synthesis    of    Palladium    Complexes    with    N- Heterocyclic Carbene Ligands and Investigation of their Catalytic Activity • Tahereh   Ghasemi   (2021-present),   Research   topic:   Synthesis   and   Characterization   of   Novel   gold(I) Complexes with N-Heterocyclic Carbene and Phosphine Ligands • Farzaneh Osanlou (2023-present), Co-advised with Dr. Shahram Seidi, Research topic: Synthesis and characterization of silver nanoclusters  

Former Ph.D. Students

• Seyyed Ali Mousavizadeh Mobarakeh (2018-2023), Thesis Title: Iron(III) Complexes of N- Heterocyclic Carbene Ligands and their Application in Transfer Hydrogenation Reactions • Shirin    Gilanchi    (2017–2022),    Thesis    Title:    Synthesis    and    Characterization    of    New    Tri-Dentate Pincer   Ligands   Based   on   N-Heterocyclic   Carbenes   and   Application   of   their   Ru(III)   Complexes   in Transfer Hydrogenation of Aldehydes and Ketones • Rasoul Safdari (2014-2020, Co-advised with Dr. M. Najafpour), Research Topic: Dye S  e  n  s  i  t  i  z  e  d    Solar Cells

Current M.Sc. Students

• Parvaneh Jabbari  (2023), Research Interests: Synthesis of Cu (II) Complexes for Catalytic “Click” Reactions • Hossein Pirmohammadi (2024), Research Interests: - Former M.Sc. Students • Mohammareza   Yousefshahi   (2019–2023),   Thesis   Title:   Metallosupramolecular   Structures   Based   on Novel ligands bearing N-heterocyclic Carbene and Schiff base Ligands • Mahdi   Cheraghi   (2020–2023),   Thesis   Title:   Novel   Poly   N-Heterocyclic   Carbene   Ligands   and   their Silver(I) Complexes • Nasrin   Aliramaei   (2019–2023),   Thesis   Title:   Synthesis   of   Nickel   N-Heterocyclic   Carbene   Complexes and investigation of their Catalytic Activity in C-S Bond Formation Reactions •    Donia   Chodari   (2020–2022),   Thesis   Title:   Structural   Characterization   and   Biological   Activities   of Novel N-Heterocyclic Carbene Gold(I) Complexes • Mahya   Keshavarzi   (2020–2022),   Thesis   Title:   Synthesis   and   Antibacterial   Properties   of   Novel   N- Heterocyclic Carbene Silver(I) Complexes • Nazila    Bigdeli    (2018–2021),    Thesis    Title:    Novel    Gold    N-Heterocyclic    Carbene    Complexes    and Investigation of their Biological Activities • Saba   Mahdavi   (2017–2020),   Thesis   Title:   Synthesis   and   Characterization   of   Manganese(III)   and Copper(II)   Schiff   Base   Complexes   and   Investigation   of   their   Catalytic   Activity   in   Alcohol   Oxidation Reactions • Farzaneh    Osanlou    (2017–2019),    Thesis    Title:    Synthesis    and    Characterization    of    Manganese(III) Schiff   Base   Complexes   with   a   Flexible   Amine   Bridge   and   Investigation   of   Their   Catalytic   Activity   in Alcohol Oxidation Reactions • Meysam   Kakavand   (2017–2019),   Thesis   Title:   Synthesis   and   Characterization   of   Asymmetrical   Schiff Base   Manganese(III)   Catalysts   and   Investigation   of   Their   Catalytic   Activity   in   Alcohol   Oxidation Reactions • Samira   Ghorbani   (2016–2019),   Thesis   Title:   Synthesis   and   Investigation   of   Photophysical   Properties of Multinuclear Cu(I) Complexes with Sulphur and Phosphine Ligands • Zohreh    Khodakarami    (2016–2019),    Thesis    Title:    Synthesis    of    N-Heterocyclic    Carbenes    and Investigation of their Coordination Chemistry with Coinage Metals • Elmira    Shiri    (2016–2018),    Thesis    Title:    Synthesis    and    Characterization    of    Multi-Nuclear    Cu(I) Complexes and Investigation of Their Photoluminescence Properties • Solmaz    Varestan    (2015–2017),    Synthesis,    Characterization    and    Investigation    of    Photophysical Properties    of    Copper(I)    Complexes    with    Dihydro    bis(2-mercapto    benzimidazolyle)    Borate    and Dihydrobis(2-mercaptobenzithiazolyl) Borate Ligands • Zahra    Mohammadi    (2015–2017),    Thesis    Title:    Synthesis    and    Characterization    of    Palladium(II) Complexes    Based    on    Schiff    Base    Ligands    Derived    from    Ortho-vanillin    and    Investigation    of Biological Properties

Journal Publications - Faculty (IASBS)

• Cheraghi, Mahdi; Neshat, Abdollah; Taghizadeh-Tabarsi, Reza; Akbari-Birgani, Shiva; Kozakiewicz- Piekarz, Anna; Rezaie, Forough; Yousefshahi, Mohammad Reza, Highly Cytotoxic Coinage Metal Complexes with Poly N-Heterocyclic Car-bene Ligands, Inorg. Chem., Under Revision. • Neshat,   A.;   Mahdavi,   A.;   Yousefshahi,   M.   R.;   Cheraghi,   M.;   Mohammadi,   S.;   Eigner,   V.;   Kucerakova, M.;   Dusek,   M.;   Kaboudin,   B.;   Halvagar,   M.   R.,   Heterobimetallic   Fe(II)–Cu(I)   Complexes   Supported   with   1,1'- Bis(diphenylphosphino)ferrocene   and   Chelating   Sulfur   Donor   Ligands:   Structural   Characterization,   DFT Analysis,   Anti-tyrosinase   Assay   and   Biological   Studies,   Journal   of   Organometallic   Chemistry ,   2024    DOI: https://doi.org/10.1016/j.jorganchem.2023.122972 • Neshat,   A.;   Kakavand,   M.;   Cheraghi,   M.;   Balmohammadi,   Y.,   Structural   Characterization   and   DFT analysis   of   Cationic   Cu(I)-Fe(II)   Complexes   and   their   Use   in   the   Green   Synthesis   of   Triazoles   in   Water, ChemistrySelect ,   2023 , 8, e202302675. • Ünver,   H.,   Kakavand,   M.   &   Neshat,   A.   Synthesis,   characterization   and   catalytic   activity   of   novel monometallic   and   bimetallic   Mn(II)   complexes   with   thiocarboxamide   and   phenanthroline   ligands.   Transit Met Chem ., 2023 , 48, 157–166. • Neshat,   A.;   Khezri,   R.;   Yousefshahi,   M.   R.;   Gholinejad,   M.;   Varmaghani,   F.,   Carbon-sulfur   Coupling Reactions    Catalyzed    by    Nickel(II)    N-Heterocyclic    Carbene    Complexes,    European    Journal    of    Inorganic Chemistry,  Eur. J. Inorg. Chem. 2023 , e202300437 .   • Kaboudin,    B.;    Esfandiari,    H.;    Kakavand,    M.;    Soharabi,    M.;    Yousefian    Amirkhiz,    E.;    Neshat,    A.; Kawazoe,    T.;    Fukaya,    H.;    Yanai,    H.,    Phosphite-Imidazole    Catalyzed    N-Formylation    and    N-Acylation    of Amines, Org. Biomol. Chem. , 2023 , 21, 8182-8189. • Neshat,   A.;   Mahdavi,   A.;   Yousefshahi,   M.   R.;   Cheraghi,   M.;   Mousavizadeh,   A.;   Mohammadi,   S.;   Eigner, V.;   Kucerakova,   M.;   Dusek,   M.;   Kaboudin,   Novel   Heteroleptic   Silver(I)   and   Gold(I)   N-Heterocyclic   Carbene Complexes:    Structural    Characterization,    Computational    Analysis,    Tyrosinase    Inhibitory    and    Biological Effects, Inorg. Chem.   2023 , 62, 41, 16710–16724. • • Neshat,   A.;   Mahdavi,   A.;   Yousefshahi,   M.   R.;   Cheraghi,   M.;   Mousavizadeh,   A.;   Mohammadi,   S.;   Eigner, V.;   Kucerakova,   M.;   Dusek,   M.;   Kaboudin,   Homobimetallic   Au(I)-Au(I)   and   Heterotrimetallic   Au(I)-Fe(II)-Au(I) Complexes    with    Dialklydithiophosphates    and    Phosphine    Ligands:    Structural    Characterization,    DFT Analysis, Tyrosinase inhibitory and Biological effects,  ACS Omega , ACS Omega 2023 , 8, 23 , 20423–20439. • Neshat,   A.;   Cheraghi,   M.;   Kucerakova,   M.;   Dusek,   M.;   Mobarakeh,   A.   M.   A   Cu(II)   Complex   Based   on   a Schiff   Base   Ligand   Derived   from   Ortho-Vanillin:   Synthesis,   DFT   Analysis   and   Catalytic   Activities.   J.   Mol. Struct.   2023 , 1274 , 134545. • Neshat,   A.;   Akbari-Birgani,   S.;   Cheraghi,   M.;   Gilanchi,   S.;   Reza   Yousefshahi,   M.   A   Novel   Heteroleptic N-Heterocyclic    Carbene    Gold(I)-Borate    Complex:    Synthesis,    DFT    Analysis    and    Cytotoxicity    Studies. Inorganica Chim. Acta   2022 , 539 , 121032. • Neshat,   A.;   Mastrorilli,   P.;   Mousavizadeh   Mobarakeh,   A.,   Recent   Advances   in   Catalysis   Involving Bidentate N-Heterocyclic Carbene Ligands. Molecules   2022 , 27 (1). • Neshat,   A.;   Gholinejad,   M.;   Özcan,   H.;   Khosravi,   F.;   Mousavizadeh,   A.;   Zaim,   Ö.,   Suzuki   Coupling Reactions   Catalyzed   by   Schiff   Base   Supported   Palladium   Complexes   Bearing   Vitamin   B6   Cofactor,   J.   Mol. Catal. , 505, 2021 , 111528. • Neshat,   A.;   Gholinejad,   M.;   Afrasi,   M.;   Mastrorilli,   P.;   Todisco,   S.;   Gilanchi,   S.;   Osanlou,   F.,   Heterocyclic thiolates   and   Phosphine   Ligands   in   Copper-Catalyzed   Synthesis   of   Propargylamines,   Appl.   Organomet. Chem. , 2021 ; e6180. • Khalili,    D.;    Evazi,    R.,    Neshat,    A.;    Aboonajmi,    J.,    Copper(I)    Complex    of    Dihydro    Bis(2-Mercapto Benzimidazolyl)   Borate   as   an   Efficient   Homogeneous   Catalyst   for   the   Synthesis   of   2H-indazoles   and   5- Substituted 1H-tetrazoles, ChemistrySelect , 2021 , 6, 746 –753. • Neshat,   A.;   Osanlou,   F.;   Kakavand,   M.;   Mastrorilli,   P;   Schingaro,   E.;   Mesto,   E.;   Todisco,   S.,   Catalytic Alcohol   Oxidation   Using   Cationic   Schiff   Base   ManganeseIII   Complexes   with   Flexible   Diamino   Bridge, Polyhedron , 2021 , 193, 114873. • Faghih,    Z.;    Neshat,    A.;    Mastrorilli,    P.;    Gallo,    V.;    Faghih,    Z.;    Gilanchi,    S.,    Cu(II),    Ni(II)    and    Co(II) Complexes             with             Homoscorpionate             Bis(2-Mercaptobenzimidazolyl)             and             Bis(2- Mercaptobenzothiazolyl)borate   Ligands:   Synthesis   and   in   Vitro   Cytotoxicity   Studies,   Inorg.   Chim.   Acta , 2020 , 512, 119896. • Khalili,   D.;   Evazi,   R.;   Neshat,   A.;   Abonajmi,   J.;   Osanlou,   F.,   Click   reactions   catalyzed   by   Cu(I)   complexes supported   with   dihydrobis(2-mercapto-benzimidazolyl)borate   and   phosphine   ligands,   Inorg.   Chim.   Acta , 2020 , 506, 119470. • Neshat,   A.;   Kakavand,   M.;   Osanlou,   F.;   Mastrorilli,   P;   Schingaro,   E.;   Mesto,   E.;   Todisco,   S,   Alcohol Oxidations by Schiff Base Manganese(III) Complexes, Eur. J. Inorg. Chem . 2020 , 2020, 480-490. • Neshat,   A.;   Afrasi,   M.;   Gilanchi,   S.;   Gholinejad,   M.,   An   Efficient   A3   Coupling   Catalyst   Based   on   a   Silver Complex     Bearing     N-heterocyclic     Carbene     and     Homoscorpionate     Bis(3-methyl-mercaptoimidazolyl) Ligands. ChemistrySelect   2019 , 4, 9268 –9273. • Neshat,    A.;    Safdari,    R.,    Enhancement    in    Dye-Sensitized    Solar    Cells    Using    Surface    Plasmon Resonance   Effects   from   Colloidal   Core-Shell   Au@SiO2   Nanoparticles.   ChemistrySelect    2019 ,   4   (17),   4995- 5001. • Neshat,   A.;   Aghakhanpour,   R.   B.;   Mastrorilli,   P.;   Todisco,   S.;   Molani,   F.;   Wojtczak,   A.,   Dinuclear   and tetranuclear      copper(I)      iodide      complexes      with      P      and      P^N      donor      ligands:      Structural      and photoluminescence studies. Polyhedron   2018 , 154, 217-228. • Neshat,      A.;      Varestan,      S.;      Halvagar,      M.      R.,      Cu(I)      complexes      of      dihydrobis(2-mercapto- benzimidazolyl)borate         and         dihydrobis(2-mercapto-benzothiazolyl)borate         ligands:         structural, photophysical and computational studies. New. J. Chem. 2018 , 42 (3), 2036-2046. • Neshat,   A.;   Shahsavari,   H.   R.;   Mastrorilli,   P.;   Todisco,   S.;   Haghighi,   M.   G.;   Notash,   B.,   A   Borane Platinum    Complex    Undergoing    Reversible    Hydride    Migration    in    Solution.    Inorg.    Chem.,     2018 ,    57    (3), 1398–1407. • Faghih,    Z.;    Neshat,    A.;    Wojtczak,    A.;    Faghih,    Z.;    Mohammadi,    Z.;    Varestan,    S.,    Palladium    (II) complexes   based   on   Schiff   base   ligands   derived   from   ortho-vanillin;   synthesis,   characterization   and cytotoxic studies. Inorg. Chim. Acta   2018 , 471, 404-412. • Gholinejad,   M.;   Neshat,   A.;   Zareh,   F.;   Nájera,   C.;   Razeghi,   M.;   Khoshnood,   A.,   Palladium   supported on   bis(indolyl)methane   functionalized   magnetite   nanoparticles   as   an   efficient   catalyst   for   copper-free Sonogashira-Hagihara reaction. Applied Catalysis A : General 2016 , 525, 31-40. • Neshat,      A.,      Synthesis,      characterization      and      photophysical      properties      of      some      3,3’- bisindolyl(aryl)methanes. RSC Advances   2016 , 6 (39), 32839-32848.

Post-Doctoral Publications (Liquid Crystal Institute, Hegmann Group, Kent State University, US)

• Gao,   Y.;   Mori,   T.;   Manning,   S.;   Zhao,   Y.;   Nielsen,   A.   d.;   Neshat,   A.;   Sharma,   A.;   Mahnen,   C.   J.;   Everson, H.   R.;   Crotty,   S.;   Clements,   R.   J.;   Malcuit,   C.;   Hegmann,   E.,   Biocompatible   3D   Liquid   Crystal   Elastomer Cell Scaffolds and Foams with Primary and Secondary Porous Architecture. ACS Macro Letters 2016, 5 (1), 4-9.   • Sharma,   A.;   Neshat,   A.;   Mahnen,   C.   J.;   Nielsen,   A.   d.;   Snyder,   J.;   Stankovich,   T.   L.;   Daum,   B.   G.; LaSpina,   E.   M.;   Beltrano,   G.;   Gao,   Y.;   Li,   S.;   Park,   B.-W.;   Clements,   R.   J.;   Freeman,   E.   J.;   Malcuit,   C.; McDonough,   J.   A.;   Korley,   L.   T.   J.;   Hegmann,   T.;   Hegmann,   E.,   Biocompatible,   Biodegradable   and Porous   Liquid   Crystal   Elastomer   Scaffolds   for   Spatial   Cell   Cultures.   Macromolecular   Bioscience 2015, 15 (2), 200-214. • Mahmoodi,   N.   M.;   Najafi,   F.;   Neshat,   A.,   Poly   (amidoamine-co-acrylic   acid)   copolymer:   Synthesis, characterization and dye removal ability. Industrial Crops and Products 2013, 42, 119-125.

Postdoctoral Patent

• A.   Neshat,   A.   Sharma,   T.   Hegmann,   E.   Hegmann,   4/15/2013,   US   PCT   61/853993   “Biodegradable   Side Chain LC Elastomers: Smart Responsive Scaffolds (SRS) for tissue regeneration”

Doctoral Publications

• Neshat,   A.;   Schmidt,   J.   A.   R.,   Derivatization   of   Niobium   Complexes   Bearing   Imido   and   Acetophenone Imine Ligands. Organometallics 2010, 29 (23), 6219-6229. • Beck,   J.   F.;   Neshat,   A.;   Schmidt,   J.   A.   R.   “Structural   Characterization   of   Novel   ortho-Lithiated   Imines.” Eur. J. Inorg. Chem., 2010, 5146-5155. • Beck,    J.    F.;    Baiz,    T.    I.;    Neshat,    A.;    Schmidt,    J.    A.    R.    “Titanium    Imido    Complexes    Utilizing Orthometallated   Derivatized   Acetophenone   and   Piperonal   Imine   Ligands:   Synthesis,   Isolation   and Characterization.” Dalton Trans., 2009, 5001-5008. • Neshat,   A.;   Seambos,   C.   L.;   Beck,   J.   F.;   Schmidt,   J.   A.   R.   “Mono-Anionic   Acetophenone   Imine   Ligands: Synthesis,   Ortho-Lithiation,   and   First   Examples   of   Group   (V)   Metal   Complexes.”   Dalton   Trans.,   2009, 4987-5000. • Hanauer,      M.;      Neshat,      A.;      Bigioni,      T.      P.,      Tris(1,10-phenanthroline-[kappa]2N,N')cobalt(III) tris(trifluoromethanesulfonate)    dihydrate.    Acta    Crystallographica    Section    C    2008,    64    (3),    m111- m113.

M.SC. Publications

• Pitcher, M. W.; Neshat, A.; Seyyidoglu, S., Formation of metastable vaterite crystals in a polymer matrix by gaseous diffusion." Journal of the Chilean Chemical Society 53, no. 2 (2008): 1525-1526. • Aghatabay, N. M.; Neshat, A.; Karabiyik, T.; Somer, M.; Haciu, D.; Dülger, B., Synthesis, characterization and antimicrobial activity of Fe(II), Zn(II), Cd(II) and Hg(II) complexes with 2,6- bis(benzimidazol-2-yl) pyridine ligand. European Journal of Medicinal Chemistry 2007, 42 (2), 205- 213. • Tavman, A.; Agh-Atabay, N. M.; Neshat, A.; Gucin, F.; Dulger, B.; Haciu, D., Structural Characterization and Antimicrobial Activity of 2-(5-H/methyl-1H-benzimidazol-2-yl)-4-bromo/nitro-phenol Ligands and their Fe(NO3)3 Complexes. Transition Metal Chemistry 2006, 31 (2), 194-200. • Tabatabaeian, K.; Mamaghani, M.; Neshat, A.; Masjedi, M., Synthesis and Spectroscopic Studies of New Substituted Dinuclear η5-4,5,6,7-Tetrahydroindenyl Ruthenium Complexes. Russian Journal of Coordination Chemistry 2003, 29 (7), 501-504.

Presentations

• Neshat,   A.   “Cu(I)   Coordination   Complexes:   Synthesis,   Applications   and   Challenges”   Joint   Chemistry Workshop, Salahaddin University, Erbil, Iraq, April 22, 2019. • Neshat,   A.   “The   Chemistry   of   Boron   Containing   Ligands   with   Late   Transition   Metals.”   2 nd    World Chemistry Conference and Exhibition, Valencia, Spain, July 09-11, 2018, (Invited Speaker) • Varestan,    S,    Neshat,    A.    “ Cu    (I)    Complexes    of    Dihydrobis(2-mercapto-benzimidazolyl)borate    and Dihydrobis(2-mercapto-benzothiazolyl)borate         Ligands:         Structural,         Photophysical         and Computational    Studies.”    19 th     Iranian    Inorganic    Chemistry    Conference,    Chemistry    and    Chemical research center of Iran (poster), 2017 • Mohammadi,   Z.,   Faghih , Z.,   Neshat,   A.   “ Palladium   (II)   Complexes   Based   on   Schiff   Base   Ligands Derived    from    ortho-Vanillin     and    Study    of    Their    Anti-cancer    Properties.”    19 th     Iranian    Inorganic Chemistry Conference, Chemistry and Chemical research center of Iran (poster), 2017   • Neshat,   A.   “ZrCl 4    Mediated   Synthesis   of   Some   3,3’-   Bisindolyl(aryl)methanes   and   Study   of   Their Photophysical   Properties.”   19 th    Iranian   Inorganic   Chemistry   Conference,   Chemistry   and   Chemical research center of Iran (poster), 2017 • Neshat,   A.   “The   Investigation   of   the   Reactivity   of   a   Platinum   Complex   Precursor   with   a   Borate   Based Ligand.”   19 th    Iranian   Inorganic   Chemistry   Conference,   Chemistry   and   Chemical   research   center   of Iran (poster), 2017 • A.   Sharma,   A.   Neshat,   Y.   Gao,   C.J.   Mahnen,   A.d.   Nielsen,   J.   Snyder,   and   E.   Hegmann,   25 th ILCC,   Dublin (Ireland), July 2014 • A.   Sharma,   A.   Neshat,   Y.   Gao,   T.   Bera,   C.J.   Mahnen,   A.d.   Nielsen,   J.   Snyder,   and   E.   Hegmann,   ACS 247th meeting, Dallas, TX (USA), March 2014 • A.   Sharma,   A.   Neshat,   Y.   Gao,   C.J.   Mahnen,   A.d.   Nielsen,   J.   Snyder,   and   E.   Hegmann,   Optics   of   Liquid Crystals Conference, Honolulu, HI (USA), October 2013 • A.    Neshat,    A.    Sharma,    T.    Stankovich,    T.    Hegmann    and    E.    Hegmann,    ACS    245th    meeting,    New Orléans, USA, April 2013 • S.   Manning,   Y.   Gao,   A.   Neshat,   and   E.   Hegmann;   ACS   248th   meeting,   San   Francisco,   CA   (USA), August 2014 • C.J.   Mahnen,   A.   Sharma,   A.   Neshat,   T.L.   Stankovich,   A.d.   Nielsen,   F.C.   Barbosa,   R.W.   Emery,   J.C. Charnas,   T.   Hegmann,   and   E.   Hegmann;   Liquid   Crystal   Institute   Prototype   Facility   Opening,   Kent, OH (USA), December 2013 • C.J.   Mahnen,   A.   Sharma,   A.   Neshat,   T.L.   Stankovich,   A.d.   Nielsen,   F.C.   Barbosa,   R.W.   Emery,   J.C. Charnas,   T.   Hegmann,   and   E.   Hegmann;   Akron’s   ACS   Chapter,   Kennedy   Center   at   Hiram   College, Akron OH (USA), October 2013 • S.   Manning,   Y.   Gao,   A.   Neshat,   and   E.   Hegmann;   10th   Annual   NE   Ohio   Undergraduate   Research Symposium, Case Western Reserve, Cleveland OH (USA), August 2013 • Sharma,   A.   Neshat,   T.   Stankovich,   B.   Daum,   A.   Nielsen,   C.   Mahnen,      T.   Hegmann,   and   E.   Hegmann; MC11 Conference, University of Warwick, Coventry (UK), July 2013 • A.   Sharma,   A.   Neshat,   T.L.   Stankovich,   B.G.   Daum,   A.d.   Nielsen,   C.J.   Mahnen,   F.C.   Barbosa,   R.W. Emery,   J.C.   Charnas,   T.   Hegmann,   and   E.   Hegmann;   GRC   on   Liquid   Crystals,   Biddeford,   ME   (USA), June 2013 • C.J.   Mahnen,   A.   Sharma,   A.   Neshat,   T.L.   Stankovich,   A.d.   Nielsen,   F.C.   Barbosa,   R.W.   Emery,   J.C. Charnas, T. Hegmann, and E. Hegmann; GRC on Liquid Crystals, Biddeford, ME (USA), June 2013 • A.   Neshat,   A.   Sharma,   A.   Nielsen,   T.   Stankovich,   C.J.   Mahnen,   T.   Hegmann,   and   Elda   Hegmann;   LC Day, Kent State University, Kent, OH (USA), November 2012. *Secured 3rd place poster prize . • University of Toledo, Department of Chemistry, PhD Defense Presentation, 2011 • University of Toledo, Department of Chemistry, 4 th  Year Presentation, 2010 • Beck,   J.   F.;   Neshat,   A.;   Baiz,   T.   I.;   Schmidt,   J.   A.   R.   “Utilization   of   Orthometalated   Acetophenone   Imine Derivatives    in    Group    4    and    5    Metal    Chemistry.”    93rd    Canadian    Chemistry    Conference    and Exhibition, Toronto, ON, May 31, 2010 • Neshat,    A.    and    Schmidt,    J.    A.    R.    “Group    V    Metal    Complexes    of    Mono-Anionic    Bidentate Acetophenone    Imine    Ligands.”    Central    Regional    Meeting    of    the    American    Chemical    Society, Cleveland, OH, May 20, 2009 • Neshat,   A.;   Schmidt,   J.   A.   R.   “Exploration   of   the   Chemistry   of   Bidentate   Acetophenone   Imine   Ligands with Group V Metals.” 238th ACS National Meeting, Washington, DC, August 17, 2009 • Neshat,   A.;   Seambos,   C.   L.;   Schmidt,   J.   A.   R.   “Synthesis   and   Characterization   of   New   Niobium   and Tantalum   Complexes   with   Orthometallated   Acetophenone   Imine   Type   Ligands.”   Ohio   Inorganic Weekend, University of Toledo, Toledo, OH, November 7, 2008 • University    of    Toledo,    Department    of    Chemistry,    2 nd     Year    Talk,    ‘Dye-sensitized    solar    cells’    (Oral Presentation), 2007