The Computer Center is on the second floor of the Physics Department (next to the Physics
computer site). This Center provides the following services to the members of the university.
Torkaman Library was established in 1993. It contains a useful combination of specialized and general
books, bilingual dictionaries, and specialized and general encyclopedias.
The Education Office comes under the Education and Research Department. Its main job is to manage the
educational affairs of the students from registration to graduation.
Protein aggregation,
Amyloid proteins,
Parkinson disease,
Mitochondrial dysfunction,
Oxidative stress,
Courses
Carbohydrate and lipid
Metabolism regulation
Biochemistry of membrane
Selected Publications
Sohrabi, T., Mirzaei-Behbahani, B., Zadali, R., Pirhaghi, M., Morozova-Roche, L. A., & Meratan, A. A. , "Common Mechanisms Underlying α-Synuclein-Induced Mitochondrial Dysfunction in Parkinson’s Disease.", Journal of Molecular Biology, 2023
Zohoorian-Abootorabi, T., Meratan, A. A., Jafarkhani, S., Muronetz, V., Haertlé, T., & Saboury, A. A. , "Modulation of cytotoxic amyloid fibrillation and mitochondrial damage of α-synuclein by catechols mediated conformational changes", Scientific Reports, 2023
Mamashli, F., Meratan, A. A., Ghasemi, A., Obeidi, N., Salmani, B., Atarod, D., ... & Saboury, A. A., "Neuroprotective Effect of Propolis Polyphenol-Based Nanosheets in Cellular and Animal Models of Rotenone-Induced Parkinson’s Disease", ACS Chemical Neuroscience, 2023
Rafiei, Y., Salmani, B., Mirzaei-Behbahani, B., Taleb, M., Meratan, A. A., Ramezani, M., ... & Rezaei-Ghaleh, N. , "Polyphenols-Based Nanosheets of Propolis Modulate Cytotoxic Amyloid Fibril Assembly of α-Synuclein", ACS Chemical Neuroscience, 2022
Zadali, R., Hassani, V., Rafiei, Y., Meratan, A. A., Mamashli, F., & Nemat-Gorgani, M., "A study on the interaction of the amyloid fibrils of α-synuclein and hen egg white lysozyme with biological membranes", Biochimica et Biophysica Acta (BBA)-Biomembranes, 2022
Meratan, A. A., Hassani, V., Mahdavi, A., & Nikfarjam, N., "Pomegranate seed polyphenol-based nanosheets as an efficient inhibitor of amyloid fibril assembly and cytotoxicity of HEWL", RSC Advances, 2022
Ramezani, M., Hesami, M. D., Rafiei, Y., Ghareghozloo, E. R., Meratan, A. A., & Nikfarjam, N., "Efficient amyloid fibrillation inhibition and remodeling of preformed fibrils of bovine insulin by propolis polyphenols-based nanosheets.", ACS Applied Bio Materials, 2021
Dehghani, Z., Meratan, A. A., Saboury, A. A., & Nemat-Gorgani, M. , "α-Synuclein fibrillation products trigger the release of hexokinase I from mitochondria: Protection by curcumin, and possible role in pathogenesis of Parkinson's disease", Biochimica et Biophysica Acta (BBA)-Biomembranes, 2020
Rostampour Ghareghozloo, E., Mahdavimehr, M., Meratan, A. A., Nikfarjam, N., Ghasemi, A., Katebi, B., & Nemat-Gorgani, M, "Role of surface oxygen-containing functional groups of graphene oxide quantum dots on amyloid fibrillation of two model proteins", PLOS ONE, 2020
Zadali, R., Ghareghozloo, E. R., Ramezani, M., Hassani, V., Rafiei, Y., Chiyaneh, S. M., & Meratan, A. A., "Interactions with and membrane permeabilization of brain mitochondria by amyloid fibrils", Journal of Visualized Experiments, 2019
Katebi, B., Mahdavimehr, M., Meratan, A. A., Ghasemi, A., & Nemat-Gorgani, M., "Protective effects of silibinin on insulin amyloid fibrillation, cytotoxicity and mitochondrial membrane damage", Archives of biochemistry and biophysics, 2018
Mahdavimehr, M., Katebi, B., & Meratan, A. A. , "Effect of fibrillation conditions on the anti-amyloidogenic properties of polyphenols and their involved mechanisms.", International journal of biological macromolecules, 2018
Mahdavimehr, M., Meratan, A. A., Ghobeh, M., Ghasemi, A., Saboury, A. A., & Nemat-Gorgani, M. , "Inhibition of HEWL fibril formation by taxifolin: mechanism of action", PLOS ONE, 2017
Ghobeh, M., Ahmadian, S., Meratan, A. A., Ebrahim‐Habibi, A., Ghasemi, A., Shafizadeh, M., & Nemat‐Gorgani, M., "Interaction of Aβ (25–35) fibrillation products with mitochondria: Effect of small‐molecule natural products.", Peptide Science, 2014
Meratan, A. A., & Nemat-Gorgani, M., "Mitochondrial membrane permeabilization upon interaction with lysozyme fibrillation products: role of mitochondrial heterogeneity.", Biochimica et Biophysica Acta (BBA)-Biomembranes, 2012
Meratan, A. A., Ghasemi, A., & Nemat-Gorgani, M. , "Membrane integrity and amyloid cytotoxicity: a model study involving mitochondria and lysozyme fibrillation products", Journal of molecular biology, 2011
