Institute for Advanced Studies in Basic Sciences (IASBS)

Contact us

Institute for Advanced Studies in Basic Sciences (IASBS)
444 Prof. Yousef Sobouti Blvd.,
Zanjan 45137-66731, Iran
Postal Code 45137-66731
F: +98 24 3315 5142
T: +98 24 3315 1000

Public Relations

Room: 160 Physics Dept.
T: +98 24 3315 3888
E: publicrelations[at]iasbs.ac.ir

Secretariat

Room: 158 Mathematics Department
T: +98 24 3315 5158
E: iasbs_z[at]iasbs.ac.ir

Research Interests

Targeting cell signaling pathways involved in radioresistance, chemoresistance, and invasiveness of cancer cells
Computational studying of protein interactions
Mathematical modeling of signaling pathways
Extraction and purification of GSK-3beta protein for structural studies

Research Keywords

Cancer Biology
DNA Repair
Mathematical Modeling
Protein-Protein Interaction

Educational Background

:Masters Field

Biophysics

:Masters Thesis Title

Purification and characterization of a low molecular weight polypeptide from the venom of scorpion Buthotus saulcyi

:PhD Field

Biophysics

:PhD Thesis Title

The study of GSK-3β protein role in the radiosensitivity of T47D breast tumor cell line

Selected Publications

Maryam Rouhani and Hamid Hadi-Alijanvand, "Effect of Lithium Drug on Binding Affinities of Glycogen Synthase Kinase-3beta to Its Network Partners: A New Computational Approach", Journal of Chemical Information and Modeling, 2021, doi: 10.1021/acs.jcim.1c00952

Maryam Rouhani, "Modeling the interplay between DNA-PK, Artemis, and ATM in non-homologous end-joining repair in G1 phase of the cell cycle", Journal of Biological Physics, Vol. 45, NO. 2, 2019, doi: 10.1007/s10867-018-9519-2

Maryam Rouhani and Samira Ramshini and Maryam Omidi, "The Psychiatric Drug Lithium Increases DNA Damage and Decreases Cell Survival in MCF-7 and MDA-MB-231 Breast Cancer Cell Lines Exposed to Ionizing Radiation", Current Molecular Pharmacology, Vol. 12, NO. 4, 2019, doi: 10.2174/1874467212666190503151753