My research interest is mainly focused on biology of cancer, in different aspects, and accordingly, I pursue different perspectives as an integrated research plan. One of the fields of the research that I am interested in is developing the CRISPR systems that provide us with the ability to perform high throughput screenings in a more reliable, efficient and informative way; and then use these systems in functional genomics to find the genes involved in cancer cell survival or their resistance to the drugs. This approach is accompanied with molecular cloning, computational biology and functional studies to acquire the list of the candidate genes that are involved in the process of interest. Enlisted candidate genes can serve as potential targets for cancer therapy that are subjects of the follow up studies to discover methods to target them with small molecules or gene therapy. Another type of the research that is within my focus is cancer signaling. Although high throughput screenings are able to provide us a substantial amount of the unbiased data, signaling studies, with their detailed structure can use the accumulated knowledge of the cancer biology to understand the role of a specific protein in tumor formation and growth. This type of the research will help us to have a better insight into the basic mechanisms of human cell biology as well as the mechanisms underlying tumor formation. And last but not the least is the cancer genetics that I am interested in. Cancer genetics is important from different points of view since it can be helpful in prevention and treatment of cancer. Knowing the genetic alternations/variations that lead to a special type of cancer and the follow up research to understand how this genetic alternation/variation leads to cancer formation can help us to define novel methods for cancer prevention and therapy.
Advanced Cell Biology
Biochemistry of Protein and Nucleic Acids
Biochemistry of Lipids and Carbohydrates
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