Shiva Akbari Birgani

Shiva Akbari Birgani

Assistant Professor

Department of Biological Sciences

Information Technology and Computer Science Building, Room 338
sh.akbari [at]


I am Shiva Akbari-Birgani an Assistant Professor of Biochemistry at IASBS, Iran. My research primarily centers on investigating the non-apoptotic functions of caspases in cellular differentiation and Epithelial-Mesenchymal transition (EMT). By studying these processes, my goal is to identify novel approaches for cancer treatment. Additionally, I am actively involved in the development of organoid/adaptive organotypic models specifically tailored for breast cancer and glioblastoma research.
Here's the list of our ongoing research projects and the students working on them:

1. Design and development of biosensors for real-time detection of cell death and cancer stem cells
MSc Students: Roya Mokhtar, Najmeh Kiani, Zahra Madadi, Amir Hossein Esmaili, Tahereh Sohrabi

2. Comparative study of differentiation and apoptosis
MSc Students: Zahra Madadi, Fatemeh Hakim, Marzieh Ajalifard, Seyed MohammadHossein Saeadimoghadam

3. Drug delivery in cancer therapy
MSc Students: Masoud Mohseni, Parviz Davoodi, Alireza Taghizadeh-Tabarsi

4. Development of organoid/organotypic models of breast cancer and glioblastoma
MSc Students: Sahar Moradi Mehr, Erfan Sefidgar, Seyed Ali Karimifard, Marzieh Ajalifard, Alireza Taghizadeh-Tabarsi, MohammadHossein SaeidiMoghadam, Mehrnaz Amjadi, Hananeh Asghari
Ph.D. student: Farzaneh Fallahi

For more information about our research, please visit my ResearchGate profile at Shiva Akbari-Birgani on ResearchGate.

Research Interests

* Understanding the molecular mechanism determining cell fate (Apoptosis/Differentiation)
* Development of organoid & organotypic models; Breast cancer and Glioblastoma

Research Keywords

Apoptosis & Cell Differentiation
Organoid & Organotypic models
Breast cancer


Molecular biology

Programmed cell death


Cell biology

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