Shiva Akbari Birgani

Shiva Akbari Birgani

Assistant Professor

Department of Biological Sciences

Information Technology and Computer Science Building, Room 338
sh.akbari [at]


I am Shiva Akbari Birgani, the assistant professor, in the Department of Biochemistry, Faculty of Life Sciences, at the Institute of Advanced Studies in Basic Sciences (IASBS). I have Ph.D. and MSc in Biochemistry. I received my Ph.D. from Tarbiat Modarres University. My Ph.D. thesis was the study of cardiomyocytic differentiation of mouse embryonic stem cells (mESCs) and its comparison with apoptosis at the molecular level. My thesis was under the supervision of Professor Saman Hosseinian from Tarbiat Modarres University and Professor Hossein Baharvand from  Royan Institute.
The main focus of my research team at IASBS is the study of cancer. One of my interests is understanding the molecular mechanism determining cell fate. To take advantage of this knowledge in gene therapy and curing cancer. The other interest is the development of a suitable three-dimensional cancer model that we can use to study our proposed therapeutic approaches in conditions closer to the human body.
ResearchGate link; Shiva Akbari-Birgani on ResearchGate
Research projects and students
1- Design and development of biosensors for real-time detection of cell death and cancer stem cells
MSc Students; Roya Mokhtar, Najmeh Kiani, Zahra Madadi, Amir Hossein Esmaili, Tahereh Sohrabi
2- Comparative study of differentiation and apoptosis
MSc Students; Zahra Madadi, Fatemeh Hakim, Marzieh Ajalifard, Seyed MohammadHossein Saeadimoghadam
3- Drug delivery in cancer therapy
MSc Students;  Masoud Mohseni, Parviz Davoodi, Alireza Taghizadeh-Tabarsi
4- Development of 3D breast cancer models
MSc Students;  Sahar Moradi Mehr, Erfan Sefidgar, Seyed Ali Karimifard, Alireza Taghizadeh-Tabarsi
Ph.D. student; Farzaneh Fallahi

Research Interests

* Understanding the molecular mechanism determining cell fate (Apoptosis/Differentiation)
* Development of the three-dimensional tumor model; Breast cancer and Glioblastoma

Research Keywords

Apoptosis, Differentiation, Three-dimensional tumor model, Breast cancer, Glioblastoma


Molecular biology

Programmed cell death


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