I am Shiva Akbari-Birgani an Assistant Professor of Biochemistry at IASBS, Iran. My research primarily centers on investigating the non-apoptotic functions of caspases in cellular differentiation and Epithelial-Mesenchymal transition (EMT). By studying these processes, my goal is to identify novel approaches for cancer treatment. Additionally, I am actively involved in the development of organoid/adaptive organotypic models specifically tailored for breast cancer and glioblastoma research. Here's the list of our ongoing research projects and the students working on them: 1. Design and development of biosensors for real-time detection of cell death and cancer stem cells MSc Students: Roya Mokhtar, Najmeh Kiani, Zahra Madadi, Amir Hossein Esmaili, Tahereh Sohrabi 2. Comparative study of differentiation and apoptosis MSc Students: Zahra Madadi, Fatemeh Hakim, Marzieh Ajalifard, Seyed MohammadHossein Saeadimoghadam 3. Drug delivery in cancer therapy MSc Students: Masoud Mohseni, Parviz Davoodi, Alireza Taghizadeh-Tabarsi 4. Development of organoid/organotypic models of breast cancer and glioblastoma MSc Students: Sahar Moradi Mehr, Erfan Sefidgar, Seyed Ali Karimifard, Marzieh Ajalifard, Alireza Taghizadeh-Tabarsi, MohammadHossein SaeidiMoghadam, Mehrnaz Amjadi, Hananeh Asghari Ph.D. student: Farzaneh Fallahi For more information about our research, please visit my ResearchGate profile at Shiva Akbari-Birgani on ResearchGate.
* Understanding the molecular mechanism determining cell fate (Apoptosis/Differentiation) * Development of organoid & organotypic models; Breast cancer and Glioblastoma
Apoptosis & Cell Differentiation Organoid & Organotypic models Breast cancer Glioblastoma
Molecular biology
Programmed cell death
Enzymology
Cell biology
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